Two young scientists (Brody and Polley) achieve fame by splicing human DNA with the DNA of different animals to create a new creature. In the process they ignore their society’s ethical and legal boundaries. The scientists name their creature "Dren," which is initially a deformed infant. However, it rapidly develops into a deadly, winged human-chimera.

According to the director: "Splice is very much about our genetic future and the way science is catching up with much of the fiction out there. "[This] is a serious film and an emotional one. And there’s sex... Very unconventional sex. The centerpiece of the movie is a creature which goes through a dramatic evolutionary process. The goal is to create something shocking but also very subtle and completely believable."div.overlay { width:1040px; height:644px; } #imgplay { margin:88px 0px 0px 190px; } #player { background:no-repeat url('/videos/news/2010/may/splice.jpg') top center; } #splash, #player, #player embed, #player object { width:560px; height:340px; }